Verbal performance buschke selective reminding test srt visual performance brief visual memory test revised bvmt r.
Theracurmin containing 90 mg of curcumin.
6 capsules equivalent to 180 mg curcumin.
The investigators expect that the volunteers receiving the curcumin supplement will show less evidence of decline after 18 months than those receiving the placebo.
The following tests were used to assess cognitive performance.
Theracurmin hp capsules containing 90 mg curcumin each that will be taken as one capsule twice daily for 6 months.
Blood samples were collected at regular intervals.
Microcrystalline cellulose vegetable capsule carbohydrate gum cellulose purified water magnesium stearate vegetable grade silica.
The study lasted for 3 weeks.
Either a placebo twice daily or the curcumin supplement theracurmin containing 90 mg of curcumin.
Cognitive performance was assessed through verbal and visual testing.
Forty subjects age 51 84 years were randomized to a bioavailable form of curcumin theracurmin containing 90 mg of curcumin twice daily n 21 or placebo n 19 for 18 months.
30 mg providing a controlled surface the colloidal dispersion 30 mg of curcumin turmeric root extract daily value not established other ingredients.
The experimental group took theracurmin containing 90 mg of curcumin twice daily i e 180 mg curcumin day for 18 months.
1 capsule equivalent to 260 mg.
Attention was assessed as a secondary outcome.
Primary outcomes were verbal buschke selective reminding test srt and visual brief visual memory test revised bvmt r memory and attention trail making a was a secondary outcome.
Subjects will be randomly assigned to one of two treatment groups.
Bioavailable curcumin normal aging memory cognition positron emission tomography highlights this is the first long term 18 months double blind placebo controlled trial of a bioavailable form of curcumin theracurmin containing 90 mg of curcumin twice daily in non demented adults.
The experimental group took theracurmin containing 90 mg of curcumin twice a day ie 180 mg curcumin day for 18 months.
This same dose was used in a successful trial of patients with mild cognitive impairment.
Individuals were asked not to consume curcumin containing food for more than 7 days prior to the study.